BioSocial Health journal 3060-6268 2 1 2025 03 17 Social determinants and mental health resilience after the pandemic: A biosocial perspective 8 11 10.34172/bshj.44 EN Sara Pourrazavi https://orcid.org/0000-0002-4036-8569 Somayeh Azimi Journal Article 10.34172/bshj.44 2024 11 11 2024 12 04 The COVID-19 pandemic revealed profound vulnerabilities in public health systems and underscored the importance of mental health resilience among diverse populations. This perspective article examines how social determinants interact with biological and environmental factors to influence mental health resilience in a post-pandemic world. Applying a biosocial lens, we argue that recovery requires integrated strategies that address both immediate and long-term needs. Key protective factors include socioeconomic stability, healthcare access (such as telehealth), social support, mental health literacy, and cultural and religious practices. Policies targeting social inequities, expanding healthcare access, and strengthening community networks are essential for fostering resilience. Future research should explore the interplay between biological predispositions and social contexts to develop effective, targeted interventions for building mental health resilience across diverse populations.